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Newest date Raw Powder Oleoylethanolamide Oea CAS 111-58-0
N-Oleoylethanolamine is a naturally occurring lipid that binds with high affinity to the PPAR-α, that may have effects on preventing and curing atherosclerosis. Report shows N-Oleoylethanolamine can turn off the switch in the central nervous system for hunger, it is conducive to modulate food intake and weight management. Moreover, N-Oleoylethanolamine also can be used for Beneficial effect on analgesic and Anti- depression.

Oleoylethanolamide (OEA) is a natural metabolite that is made in small amounts in your small intestine. OEA helps regulate hunger, weight, body fat and cholesterol by binding to a receptor known as PPAR-Alpha (Peroxisome proliferator-activated receptor alpha). In essence, OEA increases the metabolism of body fat and tells your brain that you are full and it's time to stop eating. OEA is also known to increase non-exercise related calorie expenditure.
 Oleoylethanolamide (OEA) works to activate something called PPAR and simultaneously ramps up fat-burning and decreases fat storage. When you eat, OEA levels increase and your appetite decreases when the sensory nerves that link to your brain tell it that you're full. PPAR-α is a group of ligand-activated nuclear receptor that involved in the gene expression of lipid metabolism and energyhomeostasis pathways.