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Basic Information
Product Name: | |
Synonyms: | cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl); 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone; 1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone; 1-[4-(4-{[(2S,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone; 1-acetyl-4-(4-{[(2R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)(+)-2R,4S-ketoconazole; ketoconazole |
CAS: | 65277-42-1 |
MF: | C26H28Cl2N4O4 |
MW: | 531.43 |
Product Categories: | Inhibitors;Intracellular receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids |
Description
Human vitamin A is derived from the natural food. Natural vitamin A existsin dif ferent forms. In animal tissues, vitamin A is present in the formof retinoids. However, in plants, the form of vitamin A called carotenoidsis contained in the green, orange, and yellow plant tissue. Vitamin A compoundssuch as retinol, reti nal, carotene, and so on from these foods can beconverted to vitamin A in the human body. Therefore, food is the main sourceof vitamin A.
As early as 1000 years ago, the Qian Jin Yao Fang written by Sun Simiaoin Tang Dynasty recorded that animal liver can cure night blindness. Thisis the early recognition in vitamin A supplementation. The traditionalChinese medicine books also recorded that nourishing the liver can improveeyesight.
Function and Application
Vitamin A1 (retinal) is produced from (3-carotene, which can be obtainedby fermentation of corn, soybean meal, thiamin, and oc-ionone. The dry-massafter fermentation contains 120 to 150 g product/kg.
vitamin A (Retinol) is the fat-soluble vitamin a which is required fornew cell growth and prevention of night blindness. There is no appreciableloss by heating or freezing, and it is stable in the absence of air. Sourcesinclude liver, fortified margarine, egg, and milk. Vitamin A palmitatecan be found in frozen egg substitute
Occurs preformed only in animals; metabolized from carotenoids, such β-carotene,in the intestinal mucosa. Dietary sources include liver, milk, butter,cheese, eggs and fish liver oils or as carotenoi s from fruits and vegetables.Stored primarily in the liver in esterified form; transported in the bloodby retinol binding protein (RBP). Nutritional factor